Allopurinol Intravenous and Tamoxifen Solution
Determining the interaction of Allopurinol Intravenous and Tamoxifen Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that tamoxifen may decrease the hepatic metabolism of allopurinol. In addition, the risk of hepatotoxicity may be higher with concomitant use than with either agent alone. The clinical significance is unknown. Patients receiving both agents should be monitored for hepatotoxicity.
- Shah KA, Levin J, Rosen N, Greenwald E, Zumoff B "Allopurinol hepatotoxicity potentiated by tamoxifen." N Y State J Med 82 (1982): 1745-6
Generic Name: allopurinol
Brand name: Zyloprim, Lopurin, Aloprim
Synonyms: Allopurinol
Generic Name: tamoxifen
Brand name: Soltamox, Nolvadex
Synonyms: Tamoxifen
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Allopurinol Intravenous-Tamoxifen Tablets
- Allopurinol Intravenous-Tamsulosin
- Allopurinol Intravenous-Tamsulosin Capsules
- Allopurinol Intravenous-Tamsulosin Hydrochloride
- Allopurinol Intravenous-Tandem
- Allopurinol Intravenous-Tandem Capsules
- Tamoxifen Solution-Allopurinol Tablets
- Tamoxifen Solution-Allzital
- Tamoxifen Solution-Almacone
- Tamoxifen Solution-Almotriptan
- Tamoxifen Solution-Almotriptan Malate
- Tamoxifen Solution-Alodox