Alogliptin and metformin and Midodrine
Determining the interaction of Alogliptin and metformin and Midodrine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Theoretically, the coadministration with midodrine may result in decreased clearance of drugs that are primarily eliminated by active tubular secretion such as metformin, cimetidine, ranitidine, procainamide, flecainide, quinidine, and triamterene. The proposed mechanism is competitive inhibition of renal excretion by desglymidodrine, the active metabolite of midodrine. However, clinical data are lacking and no supportive experimental evidence exists. Patients receiving midodrine in combination with drugs that undergo active tubular secretion should be monitored for excessive effects of one or both drugs.
- "Product Information. ProAmatine (midodrine)." Roberts Pharmaceutical Corporation, Eatontown, NJ.
Generic Name: alogliptin / metformin
Brand name: Kazano
Synonyms: Alogliptin and Metformin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alogliptin and metformin-Midodrine Hydrochloride
- Alogliptin and metformin-Midol
- Alogliptin and metformin-Midol Caffeine Free
- Alogliptin and metformin-Midol Complete
- Alogliptin and metformin-Midol Extended Relief
- Alogliptin and metformin-Midol IB
- Midodrine-Alogliptin and Metformin Tablets
- Midodrine-Alogliptin and pioglitazone
- Midodrine-Alogliptin and Pioglitazone Tablets
- Midodrine-Alogliptin Benzoate
- Midodrine-Aloprim
- Midodrine-Aloquin