Ambrisentan Tablets and Prilosec OTC
Determining the interaction of Ambrisentan Tablets and Prilosec OTC and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Based on in vitro data, coadministration with potent inhibitors of CYP450 3A4 and/or 2C19 may be expected to increase the plasma concentrations of ambrisentan, which is a substrate of these isoenzymes. However, administration with ketoconazole (potent CYP450 3A4 inhibitor) or omeprazole (potent CYP450 2C19 inhibitor) did not result in clinically relevant changes in ambrisentan exposure.
- "Product Information. Letairis (ambrisentan)." Gilead Sciences, Foster City, CA.
Generic Name: ambrisentan
Brand name: Letairis
Synonyms: Ambrisentan
Generic Name: omeprazole
Brand name: FIRST Omeprazole, Omeprazole + SyrSpend SF Alka, Prilosec, Prilosec OTC, Zegerid>, Prilosec, Prilosec OTC
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ambrisentan Tablets-Prilovix Cream
- Ambrisentan Tablets-Prilovix Lite Cream
- Ambrisentan Tablets-Prilovix Lite Plus Cream
- Ambrisentan Tablets-Prilovix Plus Cream
- Ambrisentan Tablets-Prilovix Ultralite
- Ambrisentan Tablets-Prilovix Ultralite Plus
- Prilosec OTC-Amcinonide
- Prilosec OTC-Amcinonide Cream and Ointment
- Prilosec OTC-Amcinonide Lotion
- Prilosec OTC-Amcinonide Ointment
- Prilosec OTC-Amcinonide topical
- Prilosec OTC-Amcinonide Topical application