Axid (Nizatidine Capsules and Tablets) and Nelfinavir Oral Powder
Determining the interaction of Axid (Nizatidine Capsules and Tablets) and Nelfinavir Oral Powder and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:There is currently no information in the medical literature regarding a potential interaction between nelfinavir and H2-receptor antagonists. Nelfinavir peak plasma concentration (Cmax), systemic exposure (AUC) and trough plasma concentration (Cmin) decreased by 37%, 36% and 39%, respectively, when nelfinavir (1250 mg twice daily) was coadministered with omeprazole (40 mg once daily 30 minutes before nelfinavir) for 4 days, presumably due to decreased solubility of nelfinavir as gastric pH increased. Although theoretically possible, it is not certain to what extent such an interaction may occur with H2-receptor antagonists, or whether it is clinically relevant. Caution may be advisable during coadministration.
- "Product Information. Viracept (nelfinavir)." Agouron Pharma Inc, La Jolla, CA.
Generic Name: nizatidine
Brand name: Axid, Axid AR, Axid Pulvules
Synonyms: Axid
Generic Name: nelfinavir
Brand name: Viracept
Synonyms: Nelfinavir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Axid (Nizatidine Capsules and Tablets)-Nelfinavir Tablets
- Axid (Nizatidine Capsules and Tablets)-Nembutal
- Axid (Nizatidine Capsules and Tablets)-Nembutal Sodium injection
- Axid (Nizatidine Capsules and Tablets)-Neo DM
- Axid (Nizatidine Capsules and Tablets)-Neo-Fradin
- Axid (Nizatidine Capsules and Tablets)-Neo-Metric
- Nelfinavir Oral Powder-Axid (Nizatidine Oral Solution)
- Nelfinavir Oral Powder-Axid AR
- Nelfinavir Oral Powder-Axid Oral Solution
- Nelfinavir Oral Powder-Axid Pulvules
- Nelfinavir Oral Powder-Axiron
- Nelfinavir Oral Powder-Axitinib