Buffered Salt and Vitamin Deficiency System
Determining the interaction of Buffered Salt and Vitamin Deficiency System and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that orally administered potassium chloride may decrease the gastrointestinal absorption of vitamin B12. The mechanism is believed to be a reduction in ileal pH by potassium chloride, which significantly decreases the activity of intrinsic factor that is necessary for vitamin B12 absorption. However, the interaction should rarely lead to clinically significant deficiency because the body (primarily the liver) usually has a copious supply of vitamin B12 that can sustain a person for several years in the absence of adequate intake. As for the treatment of B12 deficiency-related anemia, non-oral routes of administration (e.g., parenteral, intranasal, sublingual) are generally preferred, which would bypass the potential interaction.
- Palva IP, Salokannel SJ, Timonen T, Palva HL "Drug-induced malabsorption of vitamin B 12 . IV. Malabsorption and deficiency of B 12 during treatment with slow-release potassium chloride." Acta Med Scand 191 (1972): 355-7
Generic Name: potassium chloride / sodium chloride
Brand name: Buffered Salt, Thermotabs
Synonyms: n.a.
Generic Name: cyanocobalamin
Brand name: Cobolin-M, Depo-Cobolin, Vitamin B12, B-12 Dots, Nascobal, Cobal 1000, Vitamin B-12
Synonyms: Vitamin B12 Injection, Cyanocobalamin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Buffered Salt-Vitamin E
- Buffered Salt-Vitamin E (Systemic)
- Buffered Salt-Vitamin E Capsules and Tablets
- Buffered Salt-Vitamin E Chewable Tablets
- Buffered Salt-Vitamin E Oral Drops
- Buffered Salt-Vitamin E Oral Liquid
- Vitamin Deficiency System-Bumetanide
- Vitamin Deficiency System-Bumetanide Injection
- Vitamin Deficiency System-Bumetanide oral/injection
- Vitamin Deficiency System-Bumetanide Tablets
- Vitamin Deficiency System-Bumex
- Vitamin Deficiency System-Bumex Injection
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System 
Buffered Salt - Vitamin Deficiency System