Citric Acid, Sodium Citrate, and Potassium Citrate and Insulin regular, concentrated U-500
Determining the interaction of Citric Acid, Sodium Citrate, and Potassium Citrate and Insulin regular, concentrated U-500 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that potassium repletion may partially or completely reverse glucose intolerance in some patients with liver cirrhosis. The effect of insulin may be potentiated, and the risk of hypoglycemia increased. The mechanism by which potassium improves glucose tolerance has not been established, but it apparently does not involve a further increase in the already excessive insulin secretion associated with cirrhosis. The implications for glucose intolerance in patients without liver cirrhosis are not known.
- Hiatt N, Davidson MB, Bonorris G "The effect of potassium chloride infusion on insulin secretion in vivo." Horm Metab Res 4 (1972): 64-8
- Conn HO "Cirrhosis and diabetes. IV. Effect of potassium chloride administration on glucose and insulin metabolism." Am J Med Sci 259 (1970): 394-404
- DeFronzo RA, Cooke CR, Andres R, Faloona GR, Davis PJ "The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man." J Clin Invest 55 (1975): 845-55
Generic Name: citric acid / potassium citrate / sodium citrate
Brand name: Cytra-3, Polycitra, Polycitra-LC, Tricitrates, Virtrate-3
Synonyms: Citric acid, potassium citrate, and sodium citrate
Generic Name: insulin regular
Brand name: Humulin R, Myxredlin, Novolin R, HumuLIN R KwikPen
Synonyms: Insulin Regular
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Citric Acid, Sodium Citrate, and Potassium Citrate-Intal
- Citric Acid, Sodium Citrate, and Potassium Citrate-Intal Inhaler
- Citric Acid, Sodium Citrate, and Potassium Citrate-Intal Nebulizer Solution
- Citric Acid, Sodium Citrate, and Potassium Citrate-Integra (Ferrous Fumarate, Polysaccharide Iron Complex, Vitamin C, and Vitamin B3)
- Citric Acid, Sodium Citrate, and Potassium Citrate-Integra (Iron, Folic Acid, Vitamin C, and Vitamin B3)
- Citric Acid, Sodium Citrate, and Potassium Citrate-Integra F
- Insulin regular, concentrated U-500-Citroma
- Insulin regular, concentrated U-500-Citrucel
- Insulin regular, concentrated U-500-Citrucel (Methylcellulose Powder and Powder Packets)
- Insulin regular, concentrated U-500-Citrucel (Methylcellulose Tablets)
- Insulin regular, concentrated U-500-Citrucel Tablets
- Insulin regular, concentrated U-500-Cladribine