Clofibrate and Dilantin-125
Determining the interaction of Clofibrate and Dilantin-125 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Clofibrate, when coadministered with phenytoin may displace phenytoin from its protein binding sites. The clinical significance is unknown. A similar reaction may occur with other hydantoin derivatives and other fibric acid derivatives. Patients should be monitored for adverse effects. Patients should be advised to notify their physician if they experience symptoms of toxicity, including drowsiness, visual disturbances, change in mental status, seizures, nausea, or ataxia. The hydantoin dose may need to be decreased.
- "Product Information. Atromid-S (clofibrate)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Generic Name: phenytoin
Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt
Synonyms: Dilantin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Clofibrate-Dilantin-30
- Clofibrate-Dilatrate-SR
- Clofibrate-Dilaudid
- Clofibrate-Dilaudid (Hydromorphone Injection)
- Clofibrate-Dilaudid (Hydromorphone Liquid)
- Clofibrate-Dilaudid (Hydromorphone Suppository)
- Dilantin-125-Clolar
- Dilantin-125-Clomid
- Dilantin-125-Clomiphene
- Dilantin-125-Clomiphene Citrate
- Dilantin-125-Clomipramine
- Dilantin-125-Clomipramine Capsules