Cobicistat and Coumadin Injection
Determining the interaction of Cobicistat and Coumadin Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Cobicistat may alter the blood levels and effects of warfarin. You may need more frequent monitoring of your prothrombin time or INR by your doctor to safely use both medications. Let your doctor know if your condition changes or you experience unusual bleeding or bruising. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: According to the product information for cobicistat, plasma concentrations of warfarin may be altered during coadministration. The mechanism of interaction has not been described, and no pharmacokinetic data are currently available.
MANAGEMENT: The INR may need to be monitored more closely following addition or discontinuation of cobicistat, and the warfarin dosage adjusted as necessary.
- "Product Information. Stribild (cobicistat/elvitegravir/emtricitabine/tenofov)." Gilead Sciences, Foster City, CA.
Generic Name: warfarin
Brand name: Coumadin, Jantoven
Synonyms: Coumadin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cobicistat-Covaryx
- Cobicistat-Covaryx HS
- Cobicistat-Covera-HS
- Cobicistat-Cozaar
- Cobicistat-CPB WC
- Cobicistat-CPM-PSE DM Drops
- Coumadin Injection-Cobicistat and darunavir
- Coumadin Injection-Cobicistat, darunavir, emtricitabine, and tenofovir
- Coumadin Injection-Cobicistat, elvitegravir, emtricitabine, and tenofovir
- Coumadin Injection-Cobimetinib
- Coumadin Injection-Cobimetinib Fumarate
- Coumadin Injection-Cobolin-M injection