Diphenhydramine and Phenylephrine Oral Strips and Tasigna
Determining the interaction of Diphenhydramine and Phenylephrine Oral Strips and Tasigna and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Nilotinib may increase the blood levels and effects of diphenhydrAMINE. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Based on in vitro inhibition data, coadministration with nilotinib may increase the plasma concentrations of drugs that are substrates of the P-glycoprotein (P-gp) efflux transporter and/or CYP450 2D6, CYP450 3A4, or UGT1A1 isoenzymes. The mechanism is decreased clearance via these routes due to inhibition by nilotinib.
MANAGEMENT: Caution is advised when nilotinib is used concurrently with drugs that are known P-gp and/or CYP450 2D6, CYP450 3A4 or UGT1A1 substrates, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever nilotinib is added to or withdrawn from therapy.
- "Product Information. Tasigna (nilotinib)." Novartis Pharmaceuticals, East Hanover, NJ.
Generic Name: diphenhydramine / phenylephrine
Brand name: Children's Triacting Night Time, Delsym Children's Night Time Cough & Cold, Dimetapp Nighttime Cold & Congestion, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Triaminic Night Time Cold & Cough, Diphentann-D, D-Tann, Uni-Tann D, Aldex-CT, Diphenmax D, Alahist LQ, Robitussin Night Time Cough & Cold Pediatric, Robitussin Night Time Cough & Cold Children's, Delsym Children's Nighttime Cough and Cold, Zoden PD, Benadryl-D Children's Allergy & Sinus, Children's Allergy Plus Congestion, PediaCare Children's NightRest, Children's Triaminic Cough/Cold Nighttime, Theraflu Cold/Cough Nighttime
Synonyms: Diphenhydramine and phenylephrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Diphenhydramine and Phenylephrine Oral Strips-Tasimelteon
- Diphenhydramine and Phenylephrine Oral Strips-Tasmar
- Diphenhydramine and Phenylephrine Oral Strips-Tavalisse
- Diphenhydramine and Phenylephrine Oral Strips-Tavist Allergy
- Diphenhydramine and Phenylephrine Oral Strips-Tavist ND
- Diphenhydramine and Phenylephrine Oral Strips-Tavist Sinus
- Tasigna-Diphenhydramine Capsules
- Tasigna-Diphenhydramine Capsules and Tablets
- Tasigna-Diphenhydramine Chewable Tablets and Orally-Disintegrating Tablets
- Tasigna-Diphenhydramine Elixir, Liquid, and Syrup
- Tasigna-Diphenhydramine Hydrochloride
- Tasigna-Diphenhydramine Injection