Ethmozine and Leader Heartburn Relief
Determining the interaction of Ethmozine and Leader Heartburn Relief and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cimetidine together with moricizine can increase the effects of moricizine. Contact your doctor if you experience chest pain, palpitations, or irregular heartbeat. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Limited data suggest that cimetidine may inhibit the hepatic metabolism of moricizine. Bioavailability, plasma concentrations, and half-life of moricizine may be increased and may increase the risk of ECG changes (e.g., QRS and PR interval prolongation).
MANAGEMENT: The patient should be monitored for clinical and laboratory evidence of moricizine toxicity during coadministration. Patients should be advised to immediately report any chest pain, palpitations, or irregular heartbeat. A decreased dose of moricizine may be necessary. Ranitidine is not expected to interact and may be considered as an alternative to cimetidine.
- Clyne CA, Estes NA, Wang PJ "Moricizine." N Engl J Med 327 (1992): 255-60
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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