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Fomepizole and Wine

Determining the interaction of Fomepizole and Wine and the possibility of their joint administration.

Check result:

Fomepizole <> Wine

Relevance: 25.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using ethanol together with fomepizole. Ethanol and fomepizole should not be given together in the treatment of ethylene glycol poisoning. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The manufacturer reports that oral doses of fomepizole (10 to 20 mg/kg) will significantly reduce the rate of elimination of moderate doses of ethanol by approximately 40% when given to healthy volunteers. The mechanism is via alcohol dehydrogenase inhibition. By a similar mechanism, ethanol will decrease the rate of elimination of fomepizole.

MANAGEMENT: In general, ethanol and fomepizole should not be coadministered in the treatment of ethylene glycol poisoning.

References

"Product Information. Antizol (fomepizole)." Jazz Pharmaceuticals, Palo Alto, CA.

Fomepizole

Generic Name: fomepizole

Brand name: Antizol

Synonyms: n.a.

What is Fomepizole?

Wine

Generic Name: ethanol

Brand name: Ablysinol

Synonyms: n.a.

What is Wine?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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