Juxtapid and Zetia
Determining the interaction of Juxtapid and Zetia and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with lomitapide has not been shown to significantly affect the pharmacokinetics of ezetimibe. When a single 10 mg dose of ezetimibe was coadministered with lomitapide 10 mg once daily for 7 days, total ezetimibe peak plasma concentration (Cmax) increased by 3% and systemic exposure (AUC) increased by 6%. No dosage adjustment is required for ezetimibe when coadministered with lomitapide.
- "Product Information. Juxtapid (lomitapide)." Aegerion Pharmaceuticals Inc, Cambridge, MA.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.