Juxtapid Capsules and Vortioxetine Hydrobromide

• Generic Name: lomitapide
• Dosage Forms: capsule
• Other Brand Names: Juxtapid

Lomitapide is a cholesterol-lowering medication. It reduces blood levels of "bad" cholesterol, such as low-density lipoprotein (LDL) or non-high-density liproprotein (non-HDL), as well as a protein that carries bad cholesterol in the blood.

Lomitapide is used together with a low-fat diet and other treatments to lower total cholesterol in people with homozygous familial hypercholesterolemia (an inherited type of high cholesterol).

It is not known whether lomitapide will lower your risk of heart disease.

Lomitapide may also be used for purposes not listed in this medication guide.

• Generic Name: vortioxetine
• Dosage Forms: n.a.
• Other Brand Names: Trintellix, Brintellix

Treatment of major depressive disorder in adults.

APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, tricyclic antidepressants (TCAs), MAO inhibitors, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on the following factors: patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; specific properties of the medication (e.g., half-life, actions on CYP isoenzymes, other drug interactions); and cost. For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal.