Midazolam Hydrochloride and Quinidine Injection
Determining the interaction of Midazolam Hydrochloride and Quinidine Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study has suggested that quinidine may inhibit the metabolism of midazolam. The proposed mechanism for this interaction is inhibition of cytochrome P-450 (DB1). Currently this interaction is considered to be theoretical, and no clinical cases exhibiting the interaction have been reported.
- Gascon MP, Dayer P "In vitro forecasting of drugs which may interfere with the biotransformation of midazolam." Eur J Clin Pharmacol 41 (1991): 573-8
Generic Name: midazolam
Brand name: Versed, Nayzilam
Synonyms: Midazolam
Generic Name: quinidine
Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release
Synonyms: Quinidine, QuiNIDine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Midazolam Hydrochloride-Quinidine Oral, Injection, Intramuscular
- Midazolam Hydrochloride-Quinidine Sulfate
- Midazolam Hydrochloride-Quinidine Sulfate Tablets
- Midazolam Hydrochloride-Quinidine Tablets
- Midazolam Hydrochloride-Quinine
- Midazolam Hydrochloride-Quinine Sulfate
- Quinidine Injection-Midazolam injection
- Quinidine Injection-Midazolam Injection Hospira
- Quinidine Injection-Midazolam nasal
- Quinidine Injection-Midazolam Nasal Spray
- Quinidine Injection-Midazolam Syrup
- Quinidine Injection-Midodrine