Norgestimate and Ethinyl Estradiol and Topcare Arthritis Pain Relief
Determining the interaction of Norgestimate and Ethinyl Estradiol and Topcare Arthritis Pain Relief and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Oral contraceptives may decrease or delay the effects of acetaminophen by increasing glucuronidation. With the usual therapeutic dosage, concurrent administration probably results in no significant additional risk.
- Miners JO, Attwood J, Birkett DJ "Influence of sex and oral contraceptive steroids on paracetamol metabolism." Br J Clin Pharmacol 16 (1983): 503-9
- Ochs HR, Greenblatt DJ, Verburg-Ochs B, Abernethy DR, Knuchel M "Differential effects of isoniazid and oral contraceptive steroids on antipyrine oxidation and acetaminophen conjugation." Pharmacology 28 (1984): 188-95
- Abernethy DR, Divoll M, Ochs HR, Ameer B, Greenblatt DJ "Increased metabolic clearance of acetaminophen with oral contraceptive use." Obstet Gynecol 60 (1982): 338-41
Generic Name: ethinyl estradiol / norgestimate
Brand name: Estarylla, Femynor, Mono-Linyah, Mononessa, Ortho Tri-Cyclen, Previfem, Sprintec, Tri-Lo-Marzia, TriNessa, Ortho Tri-Cyclen, Ortho-Cyclen, Sprintec 28, Tri-Lo-Marzia>
Synonyms: Ethinyl estradiol and norgestimate, Ethinyl Estradiol and Norgestimate
Generic Name: acetaminophen
Brand name: Acephen, Feverall, Mapap, Actamin, Anacin AF, Apra, Bromo Seltzer, Children's Tylenol, Elixsure Fever/Pain, Medi-Tabs, Q-Pap, Silapap Childrens, Tactinal, Tempra Quicklets, Tycolene, Tylenol, Vitapap, Children's Silapap, Febrol Solution, Triaminic Fever Reducer, Genapap, Tylenol Junior, Children's Tylenol Meltaways, Junior Tylenol Meltaways, Mapap Infants, Tylenol Infants, Ofirmev, Tylenol 8 Hour, Tylenol Arthritis Pain, Tylophen
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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