Patiromer Sorbitex Calcium and Ziprasidone Hydrochloride
Determining the interaction of Patiromer Sorbitex Calcium and Ziprasidone Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR CLOSELY: Ziprasidone can cause dose-related prolongation of the QT interval. While clinical data are lacking, the coadministration of ziprasidone and agents that can produce hypokalemia and/or hypomagnesemia (e.g., potassium-wasting diuretics, amphotericin B, cation exchange resins) may result in elevated risk of ventricular arrhythmias, including ventricular tachycardia and torsade de pointes, because of additive arrhythmogenic potential. MANAGEMENT: Caution is advised when ziprasidone must be used concomitantly with medications that can cause potassium and/or magnesium disturbances. Serum electrolytes should be monitored and any abnormalities corrected prior to initiating therapy with ziprasidone. Patients should be advised to notify their physician if they experience possible signs of an electrolyte imbalance, such as weakness, lethargy, drowsiness, confusion, muscle pains or cramps, dizziness, nausea, vomiting, tachycardia, or an irregular heartbeat. References "Product Information. Geodon (ziprasidone)." Pfizer US Pharmaceuticals, New York, NY.
Professional:MONITOR CLOSELY: Ziprasidone can cause dose-related prolongation of the QT interval. While clinical data are lacking, the coadministration of ziprasidone and agents that can produce hypokalemia and/or hypomagnesemia (e.g., potassium-wasting diuretics, amphotericin B, cation exchange resins) may result in elevated risk of ventricular arrhythmias, including ventricular tachycardia and torsade de pointes, because of additive arrhythmogenic potential.
MANAGEMENT: Caution is advised when ziprasidone must be used concomitantly with medications that can cause potassium and/or magnesium disturbances. Serum electrolytes should be monitored and any abnormalities corrected prior to initiating therapy with ziprasidone. Patients should be advised to notify their physician if they experience possible signs of an electrolyte imbalance, such as weakness, lethargy, drowsiness, confusion, muscle pains or cramps, dizziness, nausea, vomiting, tachycardia, or an irregular heartbeat.
- "Product Information. Geodon (ziprasidone)." Pfizer US Pharmaceuticals, New York, NY.
Generic Name: patiromer
Brand name: Veltassa
Synonyms: Patiromer
Generic Name: ziprasidone
Brand name: Geodon
Synonyms: Ziprasidone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Patiromer Sorbitex Calcium-Ziprasidone Injection
- Patiromer Sorbitex Calcium-Ziprasidone Intramuscular
- Patiromer Sorbitex Calcium-Zipsor
- Patiromer Sorbitex Calcium-Zithromax
- Patiromer Sorbitex Calcium-Zithromax (Azithromycin Injection)
- Patiromer Sorbitex Calcium-Zithromax (Azithromycin Oral Suspension)
- Ziprasidone Hydrochloride-Pavacot
- Ziprasidone Hydrochloride-Paxil
- Ziprasidone Hydrochloride-Paxil (Paroxetine Suspension)
- Ziprasidone Hydrochloride-Paxil (Paroxetine Tablets)
- Ziprasidone Hydrochloride-Paxil CR
- Ziprasidone Hydrochloride-Pazopanib