Phenytoin Sodium, Prompt injection and Sensorcaine-MPF Spinal
Determining the interaction of Phenytoin Sodium, Prompt injection and Sensorcaine-MPF Spinal and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One in vitro study has suggested that phenytoin may displace bupivacaine from plasma protein-binding sites. Theoretically, the risk of toxicity from the local anesthetic could increase.
- Ghoneim MM, Pandya H "Plasma protein binding of bupivacaine and its interaction with other drugs in man." Br J Anaesth 46 (1974): 435-8
Generic Name: phenytoin
Brand name: Dilantin, Phenytoin Sodium, Prompt, Phenytek, Dilantin Infatabs
Synonyms: Phenytoin Sodium, Prompt (injection)
Generic Name: bupivacaine
Brand name: Bupivacaine Fisiopharma, Bupivacaine Spinal, Marcaine, Marcaine Preservative Free, Marcaine Spinal, P-Care M, ReadySharp Bupivacaine, Sensorcaine, Sensorcaine-MPF, Sensorcaine-MPF Spinal, Marcaine HCl
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Phenytoin Sodium, Prompt injection-Sensorcaine-MPF/EPINEPHrine
- Phenytoin Sodium, Prompt injection-Sensorcaine/EPINEPHrine
- Phenytoin Sodium, Prompt injection-Septa Pediatric
- Phenytoin Sodium, Prompt injection-Septocaine
- Phenytoin Sodium, Prompt injection-Septocaine with Epinephrine 1:100,000
- Phenytoin Sodium, Prompt injection-Septocaine with Epinephrine 1:200,000
- Sensorcaine-MPF Spinal-Phenytoin Suspension
- Sensorcaine-MPF Spinal-Philith
- Sensorcaine-MPF Spinal-Phillips Milk of Magnesia
- Sensorcaine-MPF Spinal-Phisohex
- Sensorcaine-MPF Spinal-Phl-Fluoxetine
- Sensorcaine-MPF Spinal-Phlemex