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Pms-Haloperidol and Serzone

Determining the interaction of Pms-Haloperidol and Serzone and the possibility of their joint administration.

Check result:

Pms-Haloperidol <> Serzone

Relevance: 04.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The manufacturer of nefazodone reports that nefazodone may decrease the plasma clearance of haloperidol by 35% without significant increases in peak plasma haloperidol concentrations. The clinical significance of this interaction is unknown. If nefazodone and haloperidol must be used together, close observation for evidence of increased haloperidol effect is recommended. The haloperidol dosage may require adjustment if an interaction is suspected.

References

"Product Information. Serzone (nefazodone)." Bristol-Myers Squibb, Princeton, NJ.

Pms-Haloperidol

Generic Name: haloperidol

Brand name: Haldol, Haldol Decanoate

Synonyms: Haloperidol

What is Pms-Haloperidol?

Serzone

Generic Name: nefazodone

Brand name: Serzone

Synonyms: n.a.

What is Serzone?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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