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Strontium Chloride SR-89 and Xpovio (80 MG Twice Weekly)

Determining the interaction of Strontium Chloride SR-89 and Xpovio (80 MG Twice Weekly) and the possibility of their joint administration.

Check result:
Strontium Chloride SR-89 <> Xpovio (80 MG Twice Weekly)
Relevance: 25.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.MONITOR: The concomitant use of bone marrow depressants and strontium-89 chloride may have additive myelosuppressive effects. MANAGEMENT: Patients should be monitored for excessive bone marrow suppression during treatment with strontium-89 chloride. Dose reductions of the other bone marrow depressants may be necessary. Patients should be advised to contact their physician if they develop signs and symptoms of myelosuppression such as pallor, dizziness, fatigue, lethargy, fainting, easy bruising or bleeding, or signs of infection such as fever, chills, sore throat, body aches, and other influenza-like symptoms. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Multum Information Services, Inc. Expert Review Panel" Cerner Multum, Inc. "Australian Product Information." O 0

Professional:

MONITOR: The concomitant use of bone marrow depressants and strontium-89 chloride may have additive myelosuppressive effects.

MANAGEMENT: Patients should be monitored for excessive bone marrow suppression during treatment with strontium-89 chloride. Dose reductions of the other bone marrow depressants may be necessary. Patients should be advised to contact their physician if they develop signs and symptoms of myelosuppression such as pallor, dizziness, fatigue, lethargy, fainting, easy bruising or bleeding, or signs of infection such as fever, chills, sore throat, body aches, and other influenza-like symptoms.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Multum Information Services, Inc. Expert Review Panel"
  • Cerner Multum, Inc. "Australian Product Information." O 0
Strontium Chloride SR-89

Generic Name: strontium-89 chloride

Brand name: Metastron

Synonyms: Strontium-89

Xpovio (80 MG Twice Weekly)

Generic Name: selinexor

Brand name: Xpovio

Synonyms: Xpovio

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.