AccessPak for HIV PEP Expanded with Viracept and Miconazole oral buccal
Determining the interaction of AccessPak for HIV PEP Expanded with Viracept and Miconazole oral buccal and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Nelfinavir may increase the blood levels and effects of miconazole. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with nelfinavir may increase the plasma concentrations of drugs that are substrates of the CYP450 3A4 isoenzyme. The mechanism is decreased clearance due to inhibition of CYP450 3A4 activity by nelfinavir.
MANAGEMENT: Caution is advised if nelfinavir must be used concurrently with medications that undergo metabolism by CYP450 3A4, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever nelfinavir is added to or withdrawn from therapy.
- "Product Information. Viracept (nelfinavir)." Agouron Pharma Inc, La Jolla, CA.
Generic Name: emtricitabine / nelfinavir / tenofovir
Brand name: AccessPak for HIV PEP Expanded with Viracept
Synonyms: n.a.
Generic Name: miconazole
Brand name: Oravig, Monistat IV, Oravig
Synonyms: Miconazole oral (buccal), Miconazole (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- AccessPak for HIV PEP Expanded with Viracept-Miconazole Powder
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- AccessPak for HIV PEP Expanded with Viracept-Miconazole vaginal
- AccessPak for HIV PEP Expanded with Viracept-Miconazole, zinc oxide, and white petrolatum Topical application
- AccessPak for HIV PEP Expanded with Viracept-MiCort-HC
- Miconazole oral buccal-Accolate
- Miconazole oral buccal-Accretropin
- Miconazole oral buccal-Accucaine
- Miconazole oral buccal-AccuHist Drops
- Miconazole oral buccal-AccuHist PDX Drops
- Miconazole oral buccal-AccuHist PDX Syrup