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Acetaminophen and pseudoephedrine and Methylphenidate

Determining the interaction of Acetaminophen and pseudoephedrine and Methylphenidate and the possibility of their joint administration.

Check result:

Acetaminophen and pseudoephedrine <> Methylphenidate

Relevance: 15.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Both pseudoephedrine and methylphenidate can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Central nervous system (CNS) stimulants, particularly the amphetamines, can potentiate the adrenergic response to vasopressors and other sympathomimetic agents. Additive increases in blood pressure and heart rate may occur due to enhanced peripheral sympathetic activity.

MANAGEMENT: Caution is advised if CNS stimulants are used with vasopressors or other sympathomimetic agents. Pulse and blood pressure should be closely monitored.

References

"Product Information. Sanorex (mazindol)" Novartis Pharmaceuticals, East Hanover, NJ.
"Product Information. Strattera (atomoxetine)." Lilly, Eli and Company, Indianapolis, IN.
Rosenblatt JE, Lake CR, van Kammen DP, Ziegler MG, Bunney WE Jr "Interactions of amphetamine, pimozide, and lithium on plasma norepineophrine and dopamine-beta-hydroxylase in schizophrenic patients." Psychiatry Res 1 (1979): 45-52
"Product Information. Tenuate (diethylpropion)" Aventis Pharmaceuticals, Swiftwater, PA.
"Product Information. Adderall (amphetamine-dextroamphetamine)" Shire Richwood Pharmaceutical Company, Florence, KY.
"Product Information. Focalin (dexmethylphenidate)." Mikart Inc, Atlanta, GA.
Cavanaugh JH, Griffith JD, Oates JA "Effect of amphetamine on the pressor response to tyramine: formation of p-hydroxynorephedrine from amphetamine in man." Clin Pharmacol Ther 11 (1970): 656

Acetaminophen and pseudoephedrine

Generic Name: acetaminophen / pseudoephedrine

Brand name: Alka-Seltzer Cold and Sinus, Allerest No Drowsiness, Bayer Select Decongestant, Benadryl Allergy Sinus Headache, Dristan Cold Non-Drowsy, Ornex, Ornex Maximum Strength, Sinarest Sinus, Sine-Off Maximum Strength, Tavist Sinus, Triaminic Softchews Allergy Sinus, Bayer Select Sinus Pain Formula, Sudafed Sinus, Contac Sinus, Sinutab Regular Strength, Tylenol Sinus Maximum Strength, Excedrin Sinus, Genapap Sinus, Mapap Sinus, Suphedrin Plus, Phenapap, Pseudoephedrine Sinus, Sinutab Maximum Strength, Sinus Maximum Strength, Tylenol Cold Infants, Suphedrin Sinus, Theraflu Sinus, Sudafed Cold and Sinus, Sudogest Sinus Maximum Strength, Children's Tylenol Sinus, Tylenol Sinus Childrens, Sudafed Sinus Headache, Sinutab Maximum Strength Non Drowsy, Tylenol Sinus Gelcap, Nexafed Sinus Pressure + Pain

Synonyms: Acetaminophen and Pseudoephedrine

What is Acetaminophen and pseudoephedrine?

Methylphenidate

Generic Name: methylphenidate

Brand name: Adhansia XR, Aptensio XR, Concerta, Cotempla XR-ODT, Jornay PM, Metadate CD, Metadate ER, Methylin, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA, Ritalin SR, Daytrana, Methylin ER

Synonyms: n.a.

What is Methylphenidate?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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