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Acetaminophen, caffeine, and magnesium salicylate and Inderal LA

Determining the interaction of Acetaminophen, caffeine, and magnesium salicylate and Inderal LA and the possibility of their joint administration.

Check result:
Acetaminophen, caffeine, and magnesium salicylate <> Inderal LA
Relevance: 09.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Two studies have suggested that propranolol may increase the pharmacologic effects of acetaminophen. The mechanism may be related to inhibition of acetaminophen metabolism. The clinical significance of this interaction is unknown.

References
  • Baraka OZ, Truman CA, Ford JM, Roberts JC "The effect of propranolol on paracetamol metabolism in man." Br J Clin Pharmacol 29 (1990): 261-4
  • Baraka OZ, Ford JM, Truman CA, Roberts CJ "Effect of propranolol on the metabolic pathways for paracetamol in man." Br J Clin Pharmacol 28 (1989): p230-1
Acetaminophen, caffeine, and magnesium salicylate

Generic Name: acetaminophen / caffeine / magnesium salicylate

Brand name: KneeRelief

Synonyms: n.a.

Inderal LA

Generic Name: propranolol

Brand name: Hemangeol, Inderal LA, Inderal XL, InnoPran XL, Inderal, InnoPran XL

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.