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Acetaminophen/Chlorpheniramine/Dextromethorphan/Phenylephrine Caps & Tabs and Efavirenz

Determining the interaction of Acetaminophen/Chlorpheniramine/Dextromethorphan/Phenylephrine Caps & Tabs and Efavirenz and the possibility of their joint administration.

Check result:
Acetaminophen/Chlorpheniramine/Dextromethorphan/Phenylephrine Caps & Tabs <> Efavirenz
Relevance: 12.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using chlorpheniramine together with dextromethorphan may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Cautious dosage titration may be required, particularly at treatment initiation. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

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Acetaminophen/Chlorpheniramine/Dextromethorphan/Phenylephrine Caps & Tabs

Generic Name: acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine

Brand name: Dimetapp Multi-Symptom Cold and Flu, GNP Tussin Night Time, Cold Head Congestion Nighttime, Cold Multi-Symptom Nighttime, Comtrex Cold & Cough Nighttime, Theraflu Severe Cold Nighttime, Tylenol Cold Head Congestion, Tylenol Children’s Plus Flu, Tylenol Children’s Plus Multi-Symptom Cold

Synonyms: Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylephrine Liquid

Efavirenz

Generic Name: efavirenz

Brand name: Sustiva

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.