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Acetaminophen, magnesium salicylate, and pamabrom and Sodium polystyrene sulfonate Rectal

Determining the interaction of Acetaminophen, magnesium salicylate, and pamabrom and Sodium polystyrene sulfonate Rectal and the possibility of their joint administration.

Check result:

Acetaminophen, magnesium salicylate, and pamabrom <> Sodium polystyrene sulfonate Rectal

Relevance: 28.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Sodium polystyrene sulfonate can bind to calcium, iron, magnesium, and other minerals in the gastrointestinal tract. This may inactivate both sodium polystyrene sulfonate and the mineral it binds to and reduce the effectiveness of both medications. To avoid or minimize the interaction, the dosing times of sodium polystyrene sulfonate and magnesium salicylate should be separated by several hours. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Simultaneous administration of cation-donating preparations may reduce the potassium exchange capability of cation-exchange resins due to binding of the cation to the resin.

MANAGEMENT: Patients should consider separating the times of administration of the cation-exchange resin and any cation-donating preparation (e.g., mineral supplements; antacids; products containing antacids such as didanosine buffered tablets or pediatric oral solution) by several hours if possible.

References

"Product Information. Resonium Calcium (calcium polystyrene sulfonate)." Sanofi-Synthelabo Canada Inc, Markham, ON.
"Product Information. Kayexalate (sodium polystyrene sulfonate)." Sanofi Winthrop Pharmaceuticals, New York, NY.

Acetaminophen, magnesium salicylate, and pamabrom

Generic Name: acetaminophen / magnesium salicylate / pamabrom

Brand name: Pamprin Cramp Formula

Synonyms: n.a.

What is Acetaminophen, magnesium salicylate, and pamabrom?

Sodium polystyrene sulfonate Rectal

Generic Name: sodium polystyrene sulfonate

Brand name: Kalexate, Kayexalate, Kionex

Synonyms: Sodium polystyrene sulfonate (Rectal)

What is Sodium polystyrene sulfonate Rectal?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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