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Actos and Phendimetrazine Extended-Release Capsules

Determining the interaction of Actos and Phendimetrazine Extended-Release Capsules and the possibility of their joint administration.

Check result:
Actos <> Phendimetrazine Extended-Release Capsules
Relevance: 12.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

As you lose weight during treatment with phendimetrazine, your dosage requirement of pioglitazone or any other diabetic medications you are receiving may change. You may need more frequent monitoring of your blood sugar and adjustment of your diabetic regimen both during and after treatment with phendimetrazine. Let your doctor know if you experience hypoglycemia, or low blood sugar. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Since weight loss may affect glycemic control and increase the risk of hypoglycemia in type 2 diabetes mellitus, patients receiving anorectic drugs may require periodic adjustments of their antidiabetic medications.

MANAGEMENT: Blood glucose should be closely monitored during weight loss treatment, and appropriate changes made to the antidiabetic drug regimen as needed. Patients should be apprised of the risk of hypoglycemia and be alert to potential signs and symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor, hunger, weakness, perspiration, palpitation, and tachycardia. For antidiabetic medications that are not glucose-dependent, reduction in the dosage should be considered to mitigate the risk of hypoglycemia.

References
  • "Product Information. Xenical (orlistat)." Roche Laboratories, Nutley, NJ.
  • "Product Information. Didrex (benzphetamine)" Pharmacia and Upjohn, Kalamazoo, MI.
  • "Product Information. Suprenza (phentermine)." Akrimax Pharmaceuticals, Cranford, NJ.
  • "Product Information. Belviq (lorcaserin)." Eisai Inc, Teaneck, NJ.
Actos

Generic Name: pioglitazone

Brand name: Actos

Synonyms: n.a.

Phendimetrazine Extended-Release Capsules

Generic Name: phendimetrazine

Brand name: Bontril, Melfiat, Bontril PDM

Synonyms: Phendimetrazine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.