Adefovir Dipivoxil and Valcyte (Valganciclovir Oral Solution)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using valGANciclovir together with adefovir can increase the blood levels or add to the side effects of either medication. Contact your doctor if you experience increased side effects or if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Theoretically, coadministration of adefovir dipivoxil with other drugs that are eliminated by active tubular secretion may result in increased plasma concentrations of adefovir and/or the coadministered drug(s). The mechanism is competitive inhibition of renal excretion. Drugs that are thought to undergo active tubular secretion include metformin, cimetidine, ranitidine, procainamide, flecainide, quinidine, triamterene, midodrine, cidofovir, acyclovir, valacyclovir, tenofovir, ganciclovir, and valganciclovir.

MANAGEMENT: Patients receiving adefovir dipivoxil in combination with other drugs that undergo active tubular secretion should be monitored for excessive pharmacologic effects of one or both drugs, and the dosages of the drugs adjusted if necessary.

Adefovir Dipivoxil

Generic Name: adefovir

Brand name: Hepsera

Synonyms: Adefovir

What is Adefovir Dipivoxil?

Valcyte (Valganciclovir Oral Solution)

Generic Name: valganciclovir

Brand name: Valcyte

Synonyms: Valcyte

What is Valcyte (Valganciclovir Oral Solution)?