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Adrenalin (Epinephrine Injection Solution) and Dextroamphetamine Extended-Release Capsules

Determining the interaction of Adrenalin (Epinephrine Injection Solution) and Dextroamphetamine Extended-Release Capsules and the possibility of their joint administration.

Check result:

Adrenalin (Epinephrine Injection Solution) <> Dextroamphetamine Extended-Release Capsules

Relevance: 18.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Both EPINEPHrine and dextroamphetamine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Central nervous system (CNS) stimulants, particularly the amphetamines, can potentiate the adrenergic response to vasopressors and other sympathomimetic agents. Additive increases in blood pressure and heart rate may occur due to enhanced peripheral sympathetic activity.

MANAGEMENT: Caution is advised if CNS stimulants are used with vasopressors or other sympathomimetic agents. Pulse and blood pressure should be closely monitored.

References

"Product Information. Sanorex (mazindol)" Novartis Pharmaceuticals, East Hanover, NJ.
"Product Information. Strattera (atomoxetine)." Lilly, Eli and Company, Indianapolis, IN.
Rosenblatt JE, Lake CR, van Kammen DP, Ziegler MG, Bunney WE Jr "Interactions of amphetamine, pimozide, and lithium on plasma norepineophrine and dopamine-beta-hydroxylase in schizophrenic patients." Psychiatry Res 1 (1979): 45-52
"Product Information. Tenuate (diethylpropion)" Aventis Pharmaceuticals, Swiftwater, PA.
"Product Information. Adderall (amphetamine-dextroamphetamine)" Shire Richwood Pharmaceutical Company, Florence, KY.
"Product Information. Focalin (dexmethylphenidate)." Mikart Inc, Atlanta, GA.
Cavanaugh JH, Griffith JD, Oates JA "Effect of amphetamine on the pressor response to tyramine: formation of p-hydroxynorephedrine from amphetamine in man." Clin Pharmacol Ther 11 (1970): 656

Adrenalin (Epinephrine Injection Solution)

Generic Name: epinephrine

Brand name: Adrenalin, Auvi-Q, Epinephrinesnap-EMS, EpiPen 2-Pak, EpiPen JR 2-Pak, EPIsnap, Symjepi, Auvi-Q Auto-injector, Primatene Mist Inhaler, Adrenaclick, EpiPen, Twinject, Primatene Mist

Synonyms: Adrenalin, Adrenalin Injection

What is Adrenalin (Epinephrine Injection Solution)?

Dextroamphetamine Extended-Release Capsules

Generic Name: dextroamphetamine

Brand name: Dexedrine Spansule, ProCentra, Zenzedi, Dexedrine, Dextrostat, Liquadd

Synonyms: Dextroamphetamine

What is Dextroamphetamine Extended-Release Capsules?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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