Alahist CF and Proventil
Determining the interaction of Alahist CF and Proventil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using phenylephrine together with albuterol may increase cardiovascular side effects such as elevations in heart rate and blood pressure or irregular heart rhythm. Talk to your doctor if you have any questions or concerns, particularly if you have a history of high blood pressure, arrhythmia, or heart disease. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of beta-2 adrenergic agonists with other adrenergic agents may potentiate the risk of cardiovascular side effects. Beta-2 adrenergic agonists can produce clinically significant cardiovascular effects including increases in pulse rate and systolic or diastolic blood pressure as well as ECG changes such as flattening of the T wave, prolongation of the QTc interval, and ST segment depression. The risk is lower when beta-2 adrenergic agonists are inhaled at normally recommended dosages. However, these effects may be more common when the drugs are administered systemically or when recommended dosages are exceeded.
MANAGEMENT: Caution is advised if beta-2 adrenergic agonists are used concomitantly with other adrenergic agents, particularly in patients with cardiovascular disorders such as coronary insufficiency, cardiac arrhythmias, hypertrophic obstructive cardiomyopathy, or hypertension. Blood pressure and heart rate should be closely monitored.
- "Product Information. Proventil (albuterol)." Schering Laboratories, Kenilworth, NJ.
- Wong CS, Pavord ID, Williams J, Britton JR, Tattersfield AE "Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma." Lancet 336 (1990): 1396-9
- "Product Information. Foradil (formoterol)" Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. Striverdi Respimat (olodaterol)." Boehringer Ingelheim, Ridgefield, CT.
- Lowe MD, Rowland E, Brown MJ, Grace AA "Beta(2) adrenergic receptors mediate important electrophysiological effects in human ventricular myocardium." Heart 86 (2001): 45-51
- "Product Information. Severent (salmeterol)." Glaxo Wellcome, Research Triangle Park, NC.
- "Product Information. Xopenex (levalbuterol)." Sepracor, Marlborough, MA.
- "Product Information. Maxair (pirbuterol)." 3M Pharmaceuticals, St. Paul, MN.
- "Product Information. Arcapta Neohaler (indacaterol)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. Brovana (arformoterol)." Sepracor Inc, Marlborough, MA.
- "Product Information. Breo Ellipta (fluticasone-vilanterol)." GlaxoSmithKline, Research Triangle Park, NC.
Generic Name: dexbrompheniramine / dextromethorphan / phenylephrine
Brand name: Alahist CF, G-P-Tuss DXP, Panatuss DXP, Supress A Pediatric, Alahist DM, Bionatuss, Supress A, Tussall, Tussall-ER, Dexall, Y-Cof DM, Panatuss Pediatric DXP
Synonyms: n.a.
Generic Name: albuterol
Brand name: Proventil HFA, ProAir HFA, ProAir RespiClick, Ventolin HFA, Accuneb, ProAir Digihaler, Proventil, VoSpire ER
Synonyms: Proventil HFA
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alahist CF-Proventil HFA
- Alahist CF-Proventil Inhalation
- Alahist CF-Proventil Repetabs
- Alahist CF-Provenza
- Alahist CF-Provera
- Alahist CF-Provera Oral
- Proventil-Alahist DM
- Proventil-Alahist DM (Brompheniramine, Dextromethorphan, and Phenylephrine)
- Proventil-Alahist DM (Dexbrompheniramine, Dextromethorphan, and Phenylephrine Liquid)
- Proventil-Alahist LQ
- Proventil-Alamag (Aluminum Hydroxide and Magnesium Hydroxide Chewable Tablets)
- Proventil-Alamag (Aluminum Hydroxide and Magnesium Hydroxide Suspension)