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Immune Globulin Injection (Subcutaneous) and Zostavax

Determining the interaction of Immune Globulin Injection (Subcutaneous) and Zostavax and the possibility of their joint administration.

Check result:

Immune Globulin Injection (Subcutaneous) <> Zostavax

Relevance: 08.03.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Immune globulin subcutaneous may interfere with the immune response to zoster vaccine live. A person who has been treated with immune globulin subcutaneous should generally not be vaccinated for several months with a live vaccine. If vaccination was given shortly before or after immune globulin subcutaneous, a revaccination may be necessary. The immunizing doctor should be informed of recent therapy with immune globulin subcutaneous so that appropriate measures and/or precautions can be taken. It is important to tell the doctor about all other medications being used, including vitamins and herbs. Do not stop using any medications without first talking to the doctor.

Professional:

ADJUST DOSING INTERVAL: The passive transfer of antibodies present in immune globulin preparations may interfere with the immune response to live vaccines.

MANAGEMENT: Varicella virus vaccine should not be given for at least 5 months, and other live vaccines should not be given for at least 3 months, after administration of immune globulin. If such vaccinations are given shortly before or after immune globulin therapy, a revaccination may be necessary. Some experts have recommended that administration of measles virus vaccine be deferred for at least 8 months following human intravenous immune globulin therapy for immunodeficiency disease; 8 to 10 months following treatment for immune thrombocytopenic purpura (ITP); and at least 11 months following treatment for Kawasaki syndrome. In the event that immune globulin and measles virus vaccine must be administered concurrently, it is advisable to separate the injection sites by as much as possible and to administer an additional dose of vaccine at the appropriate specified interval. An additional dose of live measles, mumps, or rubella vaccine is usually not needed if the vaccine was administered at least two weeks prior to immune globulin administration. Hepatitis B immune globulin has been reported to not interfere with measles vaccination, although data are limited.

References

"Product Information. Vivaglobin (immune globulin subcutaneous)." ZLB Bioplasma Inc, Glendale, CA.
"Product Information. Thymoglobulin (immune globulin intravenous)." SangStat Medical Corporation, Menlo Park, CA.
"Product Information. Bayrab (rabies immune globulin, human)." Bayer, West Haven, CT.
"Product Information. WinRho SDF (RHo (D) immune globulin)." Nabi, Boca Raton, FL.
"Product Information. Varicella Zoster Immune Globulin (varicella zoster immune globulin)." American Red Cross Blood Services, Dedham, MA.
"Product Information. Varivax (varicella virus vaccine live)." Merck & Co, Inc, West Point, PA.
"Product Information. Hyperhep B (hepatitis B immune globulin)." Talecris Biotherapeutics, Research Triangle Park, NC.
Canadian Pharmacists Association "e-CPS. Available from: URL: http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink."
"Product Information. Nabi-HB (hepatitis B immune globulin)." Allscripts Healthcare Solutions, Libertyville, IL.
"Product Information. Attenuvax (measles virus vaccine, live, attenuated)." Merck & Co, Inc, West Point, PA.
"Product Information. Cytogam (cytomegalovirus immune globulin)." CSL Behring, King of Prussia, PA.
"Interference of immune globulin with measles and rubella immunization." Eur J Pediatr 152 (1993): 536
"Product Information. BabyBIG (botulism immune globulin)." FFF Enterprises, Temecula, CA.
"Product Information. BayGam (immune globulin intramuscular)" Bayer, West Haven, CT.
"Product Information. H-BIG (hepatitis B immune globulin)." Allscripts Pharmaceutical Company, Vernon Hills, IL.
"Product Information. Imogam Rabies-HT (rabies immune globulin, human)." sanofi pasteur, Swiftwater, PA.
"Product Information. Bayhep B (hepatitis B immune globulin)." Bayer Pharmaceutical Inc, West Haven, CT.
"Product Information. HyperRHO S/D Full Dose (RHo (D) immune globulin)." Talecris Biotherapeutics, Research Triangle Park, NC.
"Product Information. Baytet (tetanus immune globulin)." Bayer, West Haven, CT.
"Product Information. Rhophylac (RHo (D) immune globulin)." ZLB Bioplasma Inc, Glendale, CA.
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Immune Globulin IV (Human). Sandoglobulin (immune globulin intravenous)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18
"Product Information. BayRHo-D (RHo (D) immune globulin)." Bayer, West Haven, CT.

Immune Globulin Injection (Subcutaneous)

Generic Name: immune globulin subcutaneous

Brand name: Cutaquig, Cuvitru, Hizentra, Vivaglobin, Xembify

Synonyms: Immune globulin (subcutaneous)

What is Immune Globulin Injection (Subcutaneous)?

Zostavax

Generic Name: zoster vaccine live

Brand name: Zostavax

Synonyms: n.a.

What is Zostavax?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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