Abacavir, dolutegravir, and lamivudine and Chantix Starting Month Box
Determining the interaction of Abacavir, dolutegravir, and lamivudine and Chantix Starting Month Box and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Dolutegravir may increase the blood levels and effects of varenicline. You may need a dose adjustment if you have been receiving varenicline and are starting treatment with dolutegravir. Likewise, if you have been receiving both medications, the dose of varenicline may need to be adjusted if dolutegravir is discontinued. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with dolutegravir may increase the plasma concentrations of drugs that are substrates of the renal organic cation transporter 2 (OCT2). Dolutegravir has been shown in vivo to inhibit tubular secretion of creatinine by inhibiting OCT2.
MANAGEMENT: Caution is advised when dolutegravir is used with drugs that are substrates of OCT2, particularly those with a narrow therapeutic range such as metformin. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever dolutegravir is added to or withdrawn from therapy.
- "Product Information. Tivicay (dolutegravir)." ViiV Healthcare, Research Triangle Park, NC.
Generic Name: abacavir / dolutegravir / lamivudine
Brand name: Triumeq
Synonyms: Abacavir, Dolutegravir, and Lamivudine
Generic Name: varenicline
Brand name: Chantix, Chantix Starter Pack, Chantix Continuing Month
Synonyms: Varenicline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box 
Abacavir, dolutegravir, - lamivudine - Chantix Starting Month Box