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Abacavir, dolutegravir, and lamivudine and Chlorpromazine

Determining the interaction of Abacavir, dolutegravir, and lamivudine and Chlorpromazine and the possibility of their joint administration.

Check result:

Abacavir, dolutegravir, and lamivudine <> Chlorpromazine

Relevance: 09.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Administration of abacavir with other agents known to use the glucuronyl transferase or alcohol dehydrogenase metabolic pathways may increase the area under the time concentration curve for both drugs. The clinical significance is unknown.

References

"Product Information. Ziagen (abacavir)." Glaxo Wellcome, Research Triangle Pk, NC.

Abacavir, dolutegravir, and lamivudine

Generic Name: abacavir / dolutegravir / lamivudine

Brand name: Triumeq

Synonyms: Abacavir, Dolutegravir, and Lamivudine

What is Abacavir, dolutegravir, and lamivudine?

Chlorpromazine

Generic Name: chlorpromazine

Brand name: Ormazine, Thorazine, Thorazine Spansule

Synonyms: ChlorproMAZINE

What is Chlorpromazine?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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