Abacavir, dolutegravir, and lamivudine and Dehydrated Alcohol Injection
Determining the interaction of Abacavir, dolutegravir, and lamivudine and Dehydrated Alcohol Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Consumption of ethanol during treatment with abacavir results in a decrease in elimination of abacavir due to the inhibition of alcohol dehydrogenase. Coadministration of alcohol 0.7 g/kg (equivalent to 5 drinks) and abacavir resulted in a 41% increase in the area under the time concentration curve and a 26% increase in elimination half life. The clinical significance of this interaction is unknown.
- "Product Information. Ziagen (abacavir)." Glaxo Wellcome, Research Triangle Pk, NC.
Generic Name: abacavir / dolutegravir / lamivudine
Brand name: Triumeq
Synonyms: Abacavir, Dolutegravir, and Lamivudine
Generic Name: ethanol
Brand name: Ablysinol
Synonyms: Alcohol
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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