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Abacavir, Lamivudine and Zidovudine Tablets and Parafon Forte DSC

Determining the interaction of Abacavir, Lamivudine and Zidovudine Tablets and Parafon Forte DSC and the possibility of their joint administration.

Check result:
Abacavir, Lamivudine and Zidovudine Tablets <> Parafon Forte DSC
Relevance: 14.12.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Administration of abacavir with other agents known to use the glucuronyl transferase or alcohol dehydrogenase metabolic pathways may increase the area under the time concentration curve for both drugs. The clinical significance is unknown.

References
  • "Product Information. Ziagen (abacavir)." Glaxo Wellcome, Research Triangle Pk, NC.
Abacavir, Lamivudine and Zidovudine Tablets

Generic Name: abacavir / lamivudine / zidovudine

Brand name: Trizivir

Synonyms: Abacavir, lamivudine, and zidovudine, Lamivudine, and Zidovudine

Parafon Forte DSC

Generic Name: chlorzoxazone

Brand name: Lorzone, Parafon Forte DSC, Paraflex, Remular-S, Relaxazone, Eze DS, Remular, Strifon Fort

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.