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Abbokinase and Cangrelor Intravenous

Determining the interaction of Abbokinase and Cangrelor Intravenous and the possibility of their joint administration.

Check result:
Abbokinase <> Cangrelor Intravenous
Relevance: 10.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using cangrelor together with urokinase may increase the risk of bleeding, including severe and life-threatening hemorrhage. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR CLOSELY: Concomitant use of cangrelor with anticoagulants, thrombolytic agents, or other antiplatelet agents may theoretically increase the risk of bleeding. According to the manufacturer, cangrelor has been formally studied with unfractionated heparin and aspirin in healthy study subjects with no evidence of a pharmacokinetic or pharmacodynamic interaction. In clinical trials, cangrelor has been coadministered with bivalirudin, low molecular weight heparin, clopidogrel, prasugrel, and ticagrelor without clinically detectable interactions.

MANAGEMENT: Caution is recommended if cangrelor must be used in patients treated with other agents that alter hemostasis. Patients should be monitored for potentially increased bleeding complications.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Kengreal (cangrelor)." The Medicines Company, Parsippany, NJ.
Abbokinase

Generic Name: urokinase

Brand name: Kinlytic, Abbokinase, Abbokinase Open-Cath

Synonyms: Abbokinase (Intravenous)

Cangrelor Intravenous

Generic Name: cangrelor

Brand name: Kengreal

Synonyms: Cangrelor

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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