Abiraterone acetate and Itraconazole Tablets
Determining the interaction of Abiraterone acetate and Itraconazole Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with ketoconazole, a potent inhibitor of CYP450 3A4, had no clinically relevant effect on the pharmacokinetics of abiraterone in healthy volunteers. Although abiraterone has been shown in vitro to be a substrate of CYP450 3A4, no particular precaution appears necessary when prescribed with potent inhibitors of CYP450 3A4.
- "Product Information. Zytiga (abiraterone)." Centocor Inc, Malvern, PA.
Generic Name: abiraterone
Brand name: Yonsa, Zytiga
Synonyms: Abiraterone, Abiraterone Acetate
Generic Name: itraconazole
Brand name: Onmel, Sporanox, Sporanox PulsePak, Tolsura
Synonyms: Itraconazole
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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