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Ablysinol and Actoplus Met

Determining the interaction of Ablysinol and Actoplus Met and the possibility of their joint administration.

Check result:
Ablysinol <> Actoplus Met
Relevance: 13.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using ethanol together with metFORMIN. Taking this combination may cause a condition called lactic acidosis. Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain. Use alcohol cautiously. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safey take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Ethanol may potentiate the effects of metformin on lactate metabolism.

MANAGEMENT: Patients should be advised to avoid excessive alcohol consumption while taking metformin and to promptly notify their physician if they experience possible signs of lactic acidosis such as malaise, myalgia, respiratory distress, hyperventilation, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms. Other antihyperglycemic agents may be more appropriate for alcoholic patients.

References
  • "Product Information. Glucophage (metformin)." Bristol-Myers Squibb, Princeton, NJ.
Ablysinol

Generic Name: ethanol

Brand name: Ablysinol

Synonyms: n.a.

Actoplus Met

Generic Name: metformin / pioglitazone

Brand name: Actoplus Met, Actoplus Met XR

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction