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Ablysinol and Isoniazid Oral, Intramuscular

Determining the interaction of Ablysinol and Isoniazid Oral, Intramuscular and the possibility of their joint administration.

Check result:
Ablysinol <> Isoniazid Oral, Intramuscular
Relevance: 13.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Isoniazid may cause liver problems, and taking it with alcohol can increase the risk. You should avoid or limit the use of alcohol while being treated with isoniazid. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Alcoholic patients have been shown to have a higher incidence of isoniazid-induced hepatotoxicity. The mechanism has not been established.

MANAGEMENT: Patients should be counseled to avoid the combination of alcohol and isoniazid and clinicians should be aware of the risk for increased hepatotoxicity in these patients.

References
  • "Product Information. INH (isoniazid)." Ciba Pharmaceuticals, Summit, NJ.
Ablysinol

Generic Name: ethanol

Brand name: Ablysinol

Synonyms: n.a.

Isoniazid Oral, Intramuscular

Generic Name: isoniazid

Brand name: Nydrazid

Synonyms: Isoniazid

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle