Ablysinol and Vibramycin Calcium
Determining the interaction of Ablysinol and Vibramycin Calcium and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Chronic alcohol consumption may enhance the elimination of doxycycline. The mechanism is induction of hepatic microsomal enzymes by alcohol. In one study, the half-life of doxycycline in six alcoholics was 10.5 hours, compared with 14.7 hours in six control patients. In addition, half the alcoholic patients had serum concentrations below what is generally considered the minimum therapeutic concentration (0.5 mcg/mL) at 12 to 24 hours after the dose. The investigators suggest that twice-a-day dosing may be indicated in these patients, especially if additional inducing drugs are used. The elimination of other tetracyclines probably is not affected by alcohol consumption.
- Neuvonen PJ, Penttila O, Roos M, Tirkkonen J "Effect of long-term alcohol consumption on the half-life of tetracycline and doxycycline in man." Int J Clin Pharmacol Biopharm 14 (1976): 303-7
Generic Name: doxycycline
Brand name: Vibramycin, Acticlate, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, Monodox, Morgidox, Oraxyl, TargaDOX, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Oracea, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, Doxy 100, TargaDOX
Synonyms: Vibramycin (Suspension), Vibramycin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ablysinol-Vibramycin Hyclate
- Ablysinol-Vicks 44 Cold, Flu and Cough
- Ablysinol-Vicks 44 Cough Relief
- Ablysinol-Vicks DayQuil Multi-Symptom
- Ablysinol-Vicks DayQuil Multi-Symptom Cold/Flu Relief
- Ablysinol-Vicks DayQuil Severe Cold/Flu
- Vibramycin Calcium-AbobotulinumtoxinA
- Vibramycin Calcium-Abobotulinumtoxina Intramuscular
- Vibramycin Calcium-Abraxane
- Vibramycin Calcium-Absorbine Jr.
- Vibramycin Calcium-Absorica
- Vibramycin Calcium-Abstral