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Ablysinol and Xyrem

Determining the interaction of Ablysinol and Xyrem and the possibility of their joint administration.

Check result:
Ablysinol <> Xyrem
Relevance: 13.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.CONTRAINDICATED: The central nervous system and respiratory depressant effects of sodium oxybate, which is the sodium salt of gamma hydroxybutyrate (GHB), may be potentiated by concomitant use of sedative-hypnotic agents. An increased risk of serious adverse reactions such as respiratory depression, hypotension, profound sedation, syncope, coma, and even death should be anticipated. MANAGEMENT: The use of sodium oxybate in combination with sedative-hypnotic agents is considered contraindicated. References "Product Information. Xyrem (sodium oxybate)." Orphan Medical, Minnetonka, MN.

Professional:

CONTRAINDICATED: The central nervous system and respiratory depressant effects of sodium oxybate, which is the sodium salt of gamma hydroxybutyrate (GHB), may be potentiated by concomitant use of sedative-hypnotic agents. An increased risk of serious adverse reactions such as respiratory depression, hypotension, profound sedation, syncope, coma, and even death should be anticipated.

MANAGEMENT: The use of sodium oxybate in combination with sedative-hypnotic agents is considered contraindicated.

References
  • "Product Information. Xyrem (sodium oxybate)." Orphan Medical, Minnetonka, MN.
Ablysinol

Generic Name: ethanol

Brand name: Ablysinol

Synonyms: n.a.

Xyrem

Generic Name: sodium oxybate

Brand name: Xyrem

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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