AbobotulinumtoxinA and Conivaptan Hydrochloride

• Generic Name: abobotulinumtoxinA
• Dosage Forms: n.a.
• Other Brand Names: Dysport

AbobotulinumtoxinA (Dysport), also called botulinum toxin type A, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.

Dysport is used to treat cervical dystonia (severe spasms in the neck muscles). Dysport is also used to treat muscle spasms (stiffness) in the upper limbs (elbows, wrists, fingers) or lower limbs (ankles, toes).

Dysport is also used to temporarily lessen the appearance of facial wrinkles.

Dysport may also be used for purposes not listed in this medication guide.

• Generic Name: conivaptan
• Dosage Forms: n.a.
• Other Brand Names: Vaprisol

Used to increase serum sodium concentrations in hospitalized patients with euvolemic or hypervolemic hyponatremia. Use in patients with hypervolemic hyponatremia associated with heart failure only after consideration of other treatment options; limited data on safety in this patient population. (See CHF under Cautions.)

Not indicated for the treatment of hypovolemic hyponatremia.

Use of conivaptan to increase serum sodium concentrations has not been established to provide symptomatic benefit to patients.

Not indicated for the treatment of CHF; efficacy not established for this indication.