AbobotulinumtoxinA and Meclizine Hydrochloride

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using abobotulinumtoxinA together with meclizine may increase certain side effects such as dry mouth, blurred vision, and urinary problems. Let your doctor know if you develop these symptoms during treatment and they do not go away after a few days or they become troublesome. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Use of anticholinergic drugs after administration of botulinum toxin may potentiate systemic anticholinergic effects such as dry mouth, blurred vision, and urinary disorders. Botulinum toxin inhibits the release of acetylcholine from peripheral cholinergic nerve endings, thus additive or synergistic anticholinergic effects may occur when these agents are used together.

MANAGEMENT: Patients should be advised that systemic anticholinergic side effects such as dry mouth, blurred vision, and urinary disorders may increase if agents with anticholinergic properties (e.g., sedating antihistamines; antispasmodics; neuroleptics; phenothiazines; skeletal muscle relaxants; tricyclic antidepressants; disopyramide) are used after administration of botulinum toxin.

AbobotulinumtoxinA

Generic Name: abobotulinumtoxinA

Brand name: Dysport

Synonyms: n.a.

What is AbobotulinumtoxinA?

Meclizine Hydrochloride

Generic Name: meclizine

Brand name: Antivert, Bonine, D-Vert, Dramamine Less Drowsy, Driminate II, Meclicot, Medivert, Ru-Vert-M, Meni-D, Travel-Ease

Synonyms: Meclizine

What is Meclizine Hydrochloride?