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Abstral and Terrell Isoflurane

Determining the interaction of Abstral and Terrell Isoflurane and the possibility of their joint administration.

Check result:
Abstral <> Terrell Isoflurane
Relevance: 22.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using fentaNYL together with isoflurane may cause low blood pressure and flushing. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Several cases of hypotension and general cutaneous flushing have been reported in patients receiving fentanyl and isoflurane. The mechanism of this interaction has not been determined.

MANAGEMENT: In general, anesthesia should be titrated to clinical effect by those experienced in anesthesia technique and in the care of patients receiving opioids.

References
  • DesMarteau JK "Isoflurane-fentanyl flush." Anesthesiology 63 (1985): 126
  • "Product Information. Ultane (sevoflurane)." Abbott Pharmaceutical, Abbott Park, IL.
Abstral

Generic Name: fentanyl

Brand name: Abstral, Fentora, Subsys, Actiq, Duragesic, Ionsys, Lazanda, Onsolis, Sublimaze

Synonyms: Abstral Sublingual Tablet

Terrell Isoflurane

Generic Name: isoflurane

Brand name: Forane, Terrell

Synonyms: Isoflurane

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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