Acarbose and Jantoven

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Limited data suggest that the anticoagulant effect of warfarin may be increased in patients also receiving acarbose. The International Normalization Ratio (INR) may increase out of the therapeutic range. The mechanism is not known, but may be related to increased absorption of warfarin. This interaction may occur with other oral anticoagulants although data is lacking. The clinician may consider closer INR and clinical monitoring in patients starting or stopping acarbose therapy while also receiving oral anticoagulants. The dose of the oral anticoagulant may need to be adjusted. Patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.

Acarbose

Generic Name: acarbose

Brand name: Precose

Synonyms: n.a.

What is Acarbose?

Jantoven

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

What is Jantoven?