Accolate and Activella Oral

• Generic Name: zafirlukast
• Dosage Forms: tablet, coated
• Other Brand Names: Accolate

Accolate is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.

Accolate is used for chronic treatment of asthma, and to prevent asthma attacks in adults and children as young as 5 years old.

Do not give Accolate to a child younger than 5 years without a doctor's advice.

Accolate may also be used for purposes not listed in this medication guide.

• Generic Name: estradiol / norethindrone
• Dosage Forms: tablet, film coated
• Other Brand Names: Activella, Mimvey, CombiPatch

Estradiol and norethindrone combination is used to treat moderate to severe hot flashes and other symptoms of menopause. It is also used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by low estrogen levels or menopause. This medicine is also used to treat certain conditions in women before menopause if their ovaries do not make enough estrogens naturally, and prevent osteoporosis after menopause.

This medicine is a combination of two hormones: an estrogen hormone (estradiol) and a progestin hormone (norethindrone). It works by preventing symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating (hot flashes) in women during menopause.

This medicine is available only with your doctor's prescription.