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AccuHist Drops and Apomorphine Hydrochloride

Determining the interaction of AccuHist Drops and Apomorphine Hydrochloride and the possibility of their joint administration.

Check result:

AccuHist Drops <> Apomorphine Hydrochloride

Relevance: 03.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using apomorphine together with chlorpheniramine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Central nervous system (CNS) depressant effects may be additively or synergistically increased in patients using apomorphine in combination with other drugs that can also cause these effects. Apomorphine alone has been frequently associated with somnolence and dizziness. Patients may suddenly fall asleep during activities of daily living.

MANAGEMENT: The use of other sedating drugs should generally be avoided during apomorphine treatment. Patients prescribed these agents concurrently should be monitored for potentially excessive or prolonged CNS depression, especially if they are elderly or debilitated. Ambulatory patients should be made aware of the possibility of additive CNS effects (e.g., drowsiness, dizziness, lightheadedness, confusion) and counseled to avoid activities requiring mental alertness until they know how these agents affect them. If patients experience increased episodes of falling asleep during normal daily activities, they should avoid driving and other potentially hazardous activities until they have contacted their physician.

References

"Product Information. Apokyn (apomorphine)." Mylan Pharmaceuticals Inc, Morgantown, WV.

AccuHist Drops

Generic Name: chlorpheniramine / phenylephrine

Brand name: Actifed Cold & Allergy, Allan Tannate Pediatric, Allerest PE, BP Allergy JR, ChlorTan D, Cold & Allergy Relief, Dallergy Drops, Ed A-Hist, Ed ChlorPed D, NoHist LQ, Phenagil, R-Tanna, Sinus & Allergy PE, Sudafed PE Sinus & Allergy, Phenylhistine, Ru-Tuss, Novahistine Elixir, Histatab Plus, Ed A-Hist LA, Rynatan Pediatric, Rynatan, Phenchlor Tannate Pediatric, Relera, Rondec Drops, Rondec, Ceron, Ceron Drops, Chlor-Mes Jr, Dallergy-JR, Rondex, Rondex Drops, Ny-Tannic, Dec-Chlorphen, Dec-Chlorphen Drops, C Phen Drops, C Phen, Tannate Pediatric, Histadec, PediaTan D, Rescon-Jr, CP Dec, Cardec Drops, P-Tann D, Triaminic Cold & Allergy, Rinate Pediatric, Cardec, AlleRx, Sildec-PE Drops, Sildec-PE, Nasohist Pediatric, PD-Hist D Drops, PD-Hist D, CP Dec Drops, Tanahist-D, Ry-Tann, Sonahist, Sinus & Allergy Maximum Strength, NoHist, Trigofen Drops, Lohist, Virdec, Maxichlor PEH, Giltuss Allergy & Sinus, Novahistine, Triaminic Cold/Allergy

Synonyms: n.a.

What is AccuHist Drops?

Apomorphine Hydrochloride

Generic Name: apomorphine

Brand name: Apokyn, APO-Go, APO-Go Pen, Uprima

Synonyms: Apomorphine

What is Apomorphine Hydrochloride?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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