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AccuHist Drops and Wakix

Determining the interaction of AccuHist Drops and Wakix and the possibility of their joint administration.

Check result:
AccuHist Drops <> Wakix
Relevance: 03.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant. MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.

Professional:

GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant.

MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
AccuHist Drops

Generic Name: chlorpheniramine / phenylephrine

Brand name: Actifed Cold & Allergy, Allan Tannate Pediatric, Allerest PE, BP Allergy JR, ChlorTan D, Cold & Allergy Relief, Dallergy Drops, Ed A-Hist, Ed ChlorPed D, NoHist LQ, Phenagil, R-Tanna, Sinus & Allergy PE, Sudafed PE Sinus & Allergy, Phenylhistine, Ru-Tuss, Novahistine Elixir, Histatab Plus, Ed A-Hist LA, Rynatan Pediatric, Rynatan, Phenchlor Tannate Pediatric, Relera, Rondec Drops, Rondec, Ceron, Ceron Drops, Chlor-Mes Jr, Dallergy-JR, Rondex, Rondex Drops, Ny-Tannic, Dec-Chlorphen, Dec-Chlorphen Drops, C Phen Drops, C Phen, Tannate Pediatric, Histadec, PediaTan D, Rescon-Jr, CP Dec, Cardec Drops, P-Tann D, Triaminic Cold & Allergy, Rinate Pediatric, Cardec, AlleRx, Sildec-PE Drops, Sildec-PE, Nasohist Pediatric, PD-Hist D Drops, PD-Hist D, CP Dec Drops, Tanahist-D, Ry-Tann, Sonahist, Sinus & Allergy Maximum Strength, NoHist, Trigofen Drops, Lohist, Virdec, Maxichlor PEH, Giltuss Allergy & Sinus, Novahistine, Triaminic Cold/Allergy

Synonyms: n.a.

Wakix

Generic Name: pitolisant

Brand name: Wakix

Synonyms: Wakix Tablets

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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