Accupril and Fosamax

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Quinapril can bind to alendronate in the gastrointestinal tract. This may inactivate alendronate or interfere with its absorption into the bloodstream, possibly reducing its effectiveness. To avoid or minimize the interaction, you should try to take them at least 2 to 3 hours apart. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: Administration of quinapril with some oral medications may significantly decrease their absorption and may result in subtherapeutic serum concentrations. The proposed mechanism is chelation of the drug by the magnesium hydroxide excipient in quinapril tablets.

MANAGEMENT: The manufacturer does not make a specific recommendation, but generally the administration of these drugs and magnesium-containing products should be separated by at least two to three hours.

Accupril

Generic Name: quinapril

Brand name: Accupril

Synonyms: n.a.

What is Accupril?

Fosamax

Generic Name: alendronate

Brand name: Binosto, Fosamax

Synonyms: n.a.

What is Fosamax?