Acella Hydrocortisone Acetate - Pramoxine Singles and Tranylcypromine Sulfate

• Generic Name: hydrocortisone / pramoxine topical
• Dosage Forms: cream
• Other Brand Names:

  Analpram-HC, Epifoam, PramCort, Pramosone, Pramosone E, ProCort, Proctofoam HC, Zone-A, Enzone, Proctocream HC, Zone-A Forte, Rectocort HC, Novacort, Hydropram, HC Pramoxine, Analpram E, ZyPram, Z-Pram, Analpram HC, PramCort, Pramasone

Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation.

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Hydrocortisone and pramoxine topical (for the skin) is a combination medicine used to treat itching and discomfort caused by allergic reactions, eczema, minor burns, insect bites, or other skin conditions.

Hydrocortisone and pramoxine rectal (for the rectum) is used to treat itching or swelling caused by hemorrhoids or other inflammatory conditions of the rectum or anus.

Hydrocortisone and pramoxine topical may also be used for other purposes not listed in this medication guide.

• Generic Name: tranylcypromine
• Dosage Forms: n.a.
• Other Brand Names: Parnate

Treatment of major depressive disorder without melancholia.

Efficacy in major depressive disorder with melancholia (endogenous features) not established.

MAO inhibitors appear particularly effective in treatment of major depressive disorder with atypical features, although other antidepressants (e.g., SSRIs) may initially be used because of their more favorable adverse effect profile.

Because of potential for serious adverse effects and necessity of dietary restrictions, MAO inhibitors (e.g., phenelzine, tranylcypromine) generally are not used as initial therapy for major depressive disorder, but are reserved for carefully selected patients who can be closely supervised and who have depression refractory to other antidepressants (e.g., SSRIs, SNRIs, TCAs) or in whom other therapies are contraindicated.