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Aceta-Gesic and Isopto Carbachol Ophthalmic Solution

Determining the interaction of Aceta-Gesic and Isopto Carbachol Ophthalmic Solution and the possibility of their joint administration.

Check result:

Aceta-Gesic <> Isopto Carbachol Ophthalmic Solution

Relevance: 25.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

DiphenhydrAMINE may reduce the effects of carbachol ophthalmic. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor

Professional:

MONITOR: Theoretically, anticholinergic agents and other agents with significant anticholinergic activity (e.g., antihistamines, antispasmodics, neuroleptics, phenothiazines, skeletal muscle relaxants, tricyclic antidepressants, class IA antiarrhythmics especially disopyramide) may antagonize the effects of topically administered cholinergic agents such as acetylcholine, carbachol, demecarium, echothiophate, isoflurophate, physostigmine, and pilocarpine. The proposed mechanism involves opposing pharmacodynamic action on muscarinic receptor sites in ocular tissue. This interaction is sometimes desirable and is the basis for using atropine in the treatment of excessive muscarinic side effects and cholinergic crisis induced by cholinergic overdose.

MANAGEMENT: Patients receiving long-term therapy with anticholinergic agents should be monitored for potentially diminished therapeutic (miotic) response to ophthalmic cholinergic therapy, and dosages adjusted as necessary.

References

"Product Information. Pilopine HS (pilocarpine ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.
"Multum Information Services, Inc. Expert Review Panel"

Aceta-Gesic

Generic Name: acetaminophen / diphenhydramine

Brand name: Aceta-Gesic, Coricidin Night Time Cold Relief, Excedrin PM, Headache Relief PM, Legatrin PM, Mapap PM, Midol PM, Night Time Pain, Pain Relief PM Extra Strength, Percogesic Extra Strength, Tylenol Cold Relief Nighttime, Tylenol PM, Tylenol Sore Throat Nighttime, Unisom with Pain Relief, Tylenol Extra Strength PM, Bayer Select Max Strength Night Time Pain, Genapap PM, Excedrin PM Caplet, Sominex Pain Relief Formula, Tylenol Severe Allergy Caplet, Anacin PM. Aspirin Free, Tylenol Extra Strength PM Vanilla, Tylenol Cold Relief Caplet, Tylenol Cold Relief Nighttime Caplet, Tylenol Extra Strength PM Rapid Release Gelcaps, Excedrin PM Express, Percogesic Original Strength, Tylenol Cold Relief, Tylenol Severe Allergy

Synonyms: n.a.

What is Aceta-Gesic?

Isopto Carbachol Ophthalmic Solution

Generic Name: carbachol ophthalmic

Brand name: Isopto Carbachol, Miostat, Carboptic, Carbastat

Synonyms: Carbachol ophthalmic, Carbachol

What is Isopto Carbachol Ophthalmic Solution?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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