Acetaminophen and Aspirin (Buffered) and Stay Awake
Determining the interaction of Acetaminophen and Aspirin (Buffered) and Stay Awake and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One study has reported that coadministration of caffeine and aspirin lead to a 25% increase in the rate of appearance and 17% increase in maximum concentration of salicylate in the plasma. A significantly higher area under the plasma concentration time curve of salicylate was also reported when both drugs were administered together. The exact mechanism of this interaction has not been specified. Physicians and patients should be aware that coadministration of aspirin and caffeine may lead to higher salicylate levels faster.
- Yoovathaworn KC, Sriwatanakul K, Thithapandha A "Influence of caffeine on aspirin pharmacokinetics." Eur J Drug Metab Pharmacokinet 11 (1986): 71-6
Generic Name: acetaminophen / aspirin
Brand name: Excedrin Back & Body
Synonyms: n.a.
Generic Name: caffeine
Brand name: Cafcit, NoDoz, Vivarin
Synonyms: Stay Awake (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Acetaminophen and Aspirin (Buffered)-Steglatro
- Acetaminophen and Aspirin (Buffered)-Steglujan
- Acetaminophen and Aspirin (Buffered)-Stelara
- Acetaminophen and Aspirin (Buffered)-Stelara (Ustekinumab Intravenous Infusion)
- Acetaminophen and Aspirin (Buffered)-Stelara (Ustekinumab Subcutaneous Injection)
- Acetaminophen and Aspirin (Buffered)-Stelazine
- Stay Awake-Acetaminophen and benzhydrocodone
- Stay Awake-Acetaminophen and butalbital
- Stay Awake-Acetaminophen and caffeine
- Stay Awake-Acetaminophen and chlorpheniramine
- Stay Awake-Acetaminophen and codeine
- Stay Awake-Acetaminophen and Codeine Oral Solution